Sinclair Method Studies
Published on: 11/06/2025
This article examines the scientific foundation behind TSM, drawing on nearly three decades of peer‑reviewed trials, neuroimaging research, and systematic reviews.
Does The Sinclair Method Work? Exploring Its Success and Science
Bruce Rose Published on: 04/09/2025
The Sinclair Method (TSM) is a medication-based treatment for Alcohol Use Disorder (AUD) that allows individuals to continue drinking while retraining their brain’s response to alcohol. The cornerstone of this method is naltrexone, an opioid blocker that dulls the endorphin rush typically triggered by alcohol.
The Sinclair Method (TSM)
